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- Yu Kurahara, Kazunobu Tachibana, Kenji Tezuka, Shigeki Shimizu, Masanori Kitaichi, Seiji Hayashi, and Katsuhiro Suzuki.
- Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan.
- Intern. Med. 2012 Jan 1; 51 (14): 1927-30.
AbstractA 28-year-old woman was referred to our hospital for treatment of tuberculous lymphadenitis, after presenting with fever, left cervical lymphadenopathy, and a positive interferon-gamma release assay (QuantiFERON®-TB Gold In-Tube; QFT) result. Surprisingly, biopsy specimens of the cervical lymph nodes showed necrotic lesions with prominent nuclear debris and a proliferation of histiocytes, consistent with Kikuchi-Fujimoto disease (KFD). A diagnosis was made of KFD complicated by latent tuberculosis infection (LTBI), and all symptoms had resolved completely two months post-diagnosis. KFD may be misdiagnosed as tuberculous lymphadenitis, and antibiotics unnecessarily prescribed. Careful attention should therefore be paid when diagnosing cervical lymphadenopathy.
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