• Canan Kucuk, Nihal Kadiogullari, Ozgur Canoler, and Serpil Savli.
• Department of Anesthesiology and Reanimation, Ankara Oncology Training and Research Hospital, Ankara, Turkey.
• Surg. Today. 2007 Jan 1;37(5):396-400.

PurposeThe aim of this study was to determine the effect of local anesthetic instillation, to compare bupivacaine and ropivacaine in patients undergoing a laparoscopic cholecystectomy.MethodsA total of 80 patients were randomly assigned to four groups to receive the intraperitoneal instillation of 21 ml of either 100 mg bupivacaine (Group B), 100 mg ropivacaine (Group R1), 150 mg ropivacaine (Group R2) or saline with epinephrine 1/200,000 at the end of the surgery. The postoperative pain was evaluated and the analgesic requirement was also assessed.ResultsThe intraperitoneal instillation of 100 mg bupivacaine, 100 mg ropivacaine, or 150 mg ropivacaine at the end of a laparoscopic cholecystectomy significantly reduced the morphine consumption during the first 24 h. For preventing postoperative pain 150 mg ropivacaine proved to be significantly more effective than either 100 mg bupivacaine or 100 mg ropivacaine.ConclusionWe herein showed that the intraperitoneal instillation of local anesthetic during laparoscopic cholecystectomy is a noninvasive, rapid, safe and simple analgesic technique that reduces the total morphine consumption during first 24 h.

17 keywords...

hide…