• Biomedica · Oct 2020

    Comparative Study

    Effects of the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) on the nervous system. What can we expect from SARS -CoV-2?

    • Jeison Monroy-Gómez and Orlando Torres-Fernández.
    • Grupo de Neurociencias Aplicadas para la Salud y el Deporte, Grupo de Capacidades Humanas en Salud e Inclusión, Institución Universitaria Escuela Colombiana de Rehabilitación, Bogotá DC, Colombia. jeison.monroy@ecr.edu.co.
    • Biomedica. 2020 Oct 30; 40 (Supl. 2): 173-179.

    AbstractCoronaviruses cause respiratory and gastrointestinal disorders in animals and humans. The current SARS-CoV-2, the COVID-19 infectious agent, belongs to a subgroup called betacoronavirus including the SARS-CoV and MERS-CoV responsible for epidemics in 2002 and 2012, respectively. These viruses can also infect the nervous system due to their affinity for the human angiotensin-converting enzyme 2 (ACE2) expressed in neurons and glial cells. Infections with SARS-CoV, MERS-CoV, and now SARS-CoV-2 also produce neurological signs such as acute cerebrovascular disease, impaired consciousness, and muscle injury, as well as dizziness, hypogeusia, hyposmia, hypoxia, neuralgia, and hypoxic encephalopathy. For this reason, close attention should be paid to the neurological manifestations of COVID-19 patients.

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