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- Joseph E Ebinger, Justyna Fert-Bober, Ignat Printsev, Min Wu, Nancy Sun, John C Prostko, Edwin C Frias, James L Stewart, Jennifer E Van Eyk, Jonathan G Braun, Susan Cheng, and Kimia Sobhani.
- Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
- Nat. Med. 2021 Jun 1; 27 (6): 981-984.
AbstractIn a cohort of BNT162b2 (Pfizer-BioNTech) mRNA vaccine recipients (n = 1,090), we observed that spike-specific IgG antibody levels and ACE2 antibody binding inhibition responses elicited by a single vaccine dose in individuals with prior SARS-CoV-2 infection (n = 35) were similar to those seen after two doses of vaccine in individuals without prior infection (n = 228). Post-vaccine symptoms were more prominent for those with prior infection after the first dose, but symptomology was similar between groups after the second dose.
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