• Antimicrob. Agents Chemother. · May 2020

    Review

    Updated Approaches against SARS-CoV-2.

    • Haiou Li, Yunjiao Zhou, Meng Zhang, Haizhou Wang, Qiu Zhao, and Jing Liu.
    • Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, China.
    • Antimicrob. Agents Chemother. 2020 May 21; 64 (6).

    AbstractNovel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in virology, epidemiology, and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing to develop a treatment for COVID-19. Recent studies have revealed many attractive therapeutic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.Copyright © 2020 American Society for Microbiology.

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