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Annals of plastic surgery · Oct 2006
Skin regeneration for children with burn scar contracture using autologous cultured dermal substitutes and superthin auto-skin grafts: preliminary clinical study.
- Yasushi Fujimori, Koichi Ueda, Hiromichi Fumimoto, Kentaro Kubo, and Yoshimitsu Kuroyanagi.
- Department of Plastic and Reconstructive Surgery, Osaka Medical College, Takatsuki, Japan. pla019@poh.osaka-med.ac.jp
- Ann Plast Surg. 2006 Oct 1;57(4):408-14.
AbstractWe have evaluated a novel treatment of burn scar contracture in children. This method involves the application of an autologous cultured dermal substitute (CDS), followed by a graft of superthin split-thickness skin. In the first operation, the autologous CDS was applied to the skin defect that had occurred after releasing the scar contracture. In the second operation, a superthin thickness skin graft (4 approximately 6/1000 inches) was applied 5 approximately 12 days after the first operation. The autologous CDS was applied to 10 sites of 5 children. On 8 sites, the skin grafts were contracted to some extent at an early stage. However, these skin grafts were stretched gradually to a range from 60% to 100% of an original size. At 2 sites, the skin grafts had stretched from 110% to 130% of the original size. This strategy may be useful for the treatment of burn scar contracture in children.
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