• Jan Latal, Michal Pazdernik, Maria Holicka, Radek Pelouch, Jiri Widimsky, Jiri Pudich, Radek Vancata, Michal Siranec, Kamila Blechova, Tadeas Butta, Marketa Mikulcova, Michal Mikulica, Peter Wohlfahrt, Martin Hutyra, and Jan Precek.
• Department of Internal Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.
• Biomed Pap. 2021 Mar 22.

AimUnderstanding cardiac electronic device infective endocarditis epidemiology is essential for the management of this serious complication. Only monocentric and limited data have been published regarding patients in the Czech republic so far. The aim of this study was to describe the current profile, microbiology and clinical characteristics of this population.Patients And MethodsNational data from the prospective ESC-EORP EURO-ENDO registry were collected. 57 consecutive patients with a diagnosis of cardiac device-related infective endocarditis (CDRIE) from 11 Czech centres were included.ResultsStaphylococcus spp. was responsible for 43.9% of isolates, whereas Culture negative endocarditis was documented in 26.3% episodes. The most frequent complications under therapy were acute renal failure (17.5%), septic shock and heart failure (both 10.5%). Extraction of device was performed in 75.4% of all patients, and the 1-year mortality was 22.5%.ConclusionsThe high proportion of culture-negative endocarditis is alarming and warrants further investigation. Cardiac device related infective endocarditis is a serious complication with a high 1-year mortality in a highly polymorbid spectrum of patients.

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