To develop and evaluate a practical B 1 + correction method for prostate dynamic contrast-enhanced (DCE) MRI analysis. ⋯ The approximated analytical B 1 + correction method provides comparable results with less than 0.2% error within 95% central range, compared to reference numerical B 1 + correction. The proposed method is a practical solution for B 1 + correction in prostate DCE-MRI because of its simple implementation.
or not…
Magn Reson Med. 2018 Dec 1; 80 (6): 2525-2537.
Purpose To develop and evaluate a practical http://www.w3.org/1998/Math/MathML"> B 1 + correction method for prostate dynamic contrast-enhanced (DCE) MRI analysis.Theory We proposed a simple analytical http://www.w3.org/1998/Math/MathML"> B 1 + correction method using a Taylor series approximation to the steady-state spoiled gradient echo signal equation. This approach only requires http://www.w3.org/1998/Math/MathML"> B 1 + maps and uncorrected pharmacokinetic (PK) parameters as input to estimate the corrected PK parameters.Methods The proposed method was evaluated using a prostate digital reference object (DRO), and 82 in vivo prostate DCE-MRI cases. The approximated analytical correction was compared with the ground truth PK parameters in simulation, and compared with the reference numerical correction in in vivo experiments, using percentage error as the metric.Results The prostate DRO results showed that our approximated analytical approach provided residual error less than 0.4% for both Ktrans and ve , compared to the ground truth. This noise-free residual error was smaller than the noise-induced error using the reference numerical correction, which had a minimum error of 2.1+4.3% with baseline signal-to-noise ratio of 234.5. For the 82 in vivo cases, Ktrans and ve percentage error compared to the reference numerical correction method had a mean of 0.1% (95% central range of [0.0%, 0.2%]) across the prostate volume.Conclusion The approximated analytical http://www.w3.org/1998/Math/MathML"> B 1 + correction method provides comparable results with less than 0.2% error within 95% central range, compared to reference numerical http://www.w3.org/1998/Math/MathML"> B 1 + correction. The proposed method is a practical solution for http://www.w3.org/1998/Math/MathML"> B 1 + correction in prostate DCE-MRI because of its simple implementation.© 2018 International Society for Magnetic Resonance in Medicine.
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