• La Tunisie médicale · Nov 2008

    Case Reports

    Fanconi anemia complicated by neutropenic enterocolitis.

    • Faten Tinsa, Nesrine Necib, Manef Guesmi, Olfa Bousnina, Wiem Douira, Khadija Bousetta, and Souad Bousnina.
    • Department of Pediatrics B, Children's Hospital of Tunis, Tunis, Tunisia.
    • Tunis Med. 2008 Nov 1; 86 (11): 1011-3.

    BackgroundNeutropenic enterocolitis (NEC) also known as typhlitis is an acute, life-threatening inflammation of the small and large bowel often seen in patients with leukaemia undergoing cytotoxic chemotherapy: occasionally this syndrome could present in other immunocompromised patients.AimTo report an unusual case of Fanconi anemia complicated by neutropenic enterocolitis.Case ReportWe report a case of a 13-year-old boy affected by Fanconi anemia with severe neutropenia and who presented neutropenic enterocolitis. Abdominal ultrasonography showed thickening of cecum and ascending colon of 1.18cm. The outcome was favourable with medical management.ConclusionNeutropenic enterocolitis in Fanconi anemia is a rare and a severe illness: however, the outcome is improved with early management.

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