A novel percutaneous mechanical biventricular bridge to

J. Heart Lung Transplant. · Jan 2010

Case Reports

A novel percutaneous mechanical biventricular bridge to recovery in severe cardiac allograft rejection.

We describe the case of a 36-year-old man with acute cardiac transplant rejection bridged to recovery using simultaneous Impella 2.5 and TandemHeart percutaneous support devices. The patient underwent orthotopic cardiac transplantation 2 years earlier, and presented to our hospital with allograft failure 7 days after non-compliance with tacrolimus. ⋯ After a course of intravenous solumedrol and anti-thymocyte globulin, both the Impella and TandemHeart devices were successfully weaned and removed. Nine months later, his left ventricular ejection fraction had stabilized from 10% to 55%.

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- Vivek Rajagopal, Gregg Steahr, Charles I Wilmer, and Nirav Y Raval.
- Piedmont Heart Institute, Piedmont Hospital, Atlanta, Georgia 30309, USA. vraj02@yahoo.com
- J. Heart Lung Transplant. 2010 Jan 1; 29 (1): 93-5.
AbstractWe describe the case of a 36-year-old man with acute cardiac transplant rejection bridged to recovery using simultaneous Impella 2.5 and TandemHeart percutaneous support devices. The patient underwent orthotopic cardiac transplantation 2 years earlier, and presented to our hospital with allograft failure 7 days after non-compliance with tacrolimus. Because of persistent cardiogenic shock despite intra-aortic balloon and inotropic support, we implanted an Impella 2.5 percutaneous assist device for left ventricular support. Persistent right ventricular dysfunction necessitated insertion of a TandemHeart for right ventricular support. After a course of intravenous solumedrol and anti-thymocyte globulin, both the Impella and TandemHeart devices were successfully weaned and removed. Nine months later, his left ventricular ejection fraction had stabilized from 10% to 55%.Copyright (c) 2010 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

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A novel percutaneous mechanical biventricular bridge to recovery in severe cardiac allograft rejection.

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