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Clin. Exp. Nephrol. · Feb 2009
Case ReportsFocal segmental glomerulosclerosis complicating solitary kidney.
- Yoshiyuki Oshiro, Sachio Umena, and Masatoshi Noda.
- Department of Internal Medicine, Kawasaki Medical School Kawasaki Hospital, 2-1-80 Nakasange, Okayama, Japan. y.oshiro@kawasaki-hp.jp.
- Clin. Exp. Nephrol. 2009 Feb 1; 13 (1): 81-4.
AbstractA 78-year old woman with complicating solitary kidney had nephrotic syndrome. Renal biopsy specimens showed focal segmental glomerulosclerosis (FSGS). First, the patient was treated with angiotensin receptor blocker (ARB) and angiotensin converting enzyme inhibitor (ACEI). Proteinuria decreased from 10 to 6 g/day, but overall the nephrotic syndrome did not improve. Additional treatment with prednisolone and cyclosporine reduced proteinuria to less than 1.0 g/day. We report that combination therapy with ARB, ACEI, prednisolone, and cyclosporine was successful for FSGS complicating solitary kidney.
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