First report of a successful pediatric heart transplantation

J. Heart Lung Transplant. · Oct 2019

Case Reports

First report of a successful pediatric heart transplantation from donation after circulatory death with distant procurement using normothermic regional perfusion and cold storage.

Heart transplantation (HT) from donation after circulatory death (DCD) is a promising alternative to expand the heart donor pool. Cold storage can be used in a strategy to successfully retrieve and transplant DCD hearts after reconditioning using normothermic regional perfusion for distant procurement. Herein, we present the first report of a pediatric DCD heart reconditioned with normothermic regional perfusion, preserved using only cold storage while being transported to a neighboring center, and then successfully transplanted after nearly 2 hours of cold static storage. If supported by an appropriate trial, this finding could obviate the need to use expensive perfusion devices for short interhospital distances for DCD heart transportation and stimulate more centers across the world to embrace DCD HT.

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- Vincent Tchana-Sato, Didier Ledoux, Katrien Vandendriessche, Johan Van Cleemput, Gregory Hans, Arnaud Ancion, Bjorn Cools, Philippe Amabili, Olivier Detry, Paul Bernard Massion, Josee Monard, Marie-Hélène Delbouille, Bart Meyns, Jean Olivier Defraigne, and Filip Rega.
- Department of Cardiovascular Surgery, CHU Liege, Liege, Belgium. Electronic address: vtchanasato@chuliege.be.
- J. Heart Lung Transplant. 2019 Oct 1; 38 (10): 1112-1115.
AbstractHeart transplantation (HT) from donation after circulatory death (DCD) is a promising alternative to expand the heart donor pool. Cold storage can be used in a strategy to successfully retrieve and transplant DCD hearts after reconditioning using normothermic regional perfusion for distant procurement. Herein, we present the first report of a pediatric DCD heart reconditioned with normothermic regional perfusion, preserved using only cold storage while being transported to a neighboring center, and then successfully transplanted after nearly 2 hours of cold static storage. If supported by an appropriate trial, this finding could obviate the need to use expensive perfusion devices for short interhospital distances for DCD heart transportation and stimulate more centers across the world to embrace DCD HT.Copyright © 2019 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

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First report of a successful pediatric heart transplantation from donation after circulatory death with distant procurement using normothermic regional perfusion and cold storage.

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