• Cahiers d'anesthésiologie · Jan 1985

    Randomized Controlled Trial Clinical Trial

    [Spinal anesthesia and morphine analgesia in prostatic surgery].

    • C Mora, J L Dupuis, and P Feiss.
    • Cah Anesthesiol. 1985 Jan 1; 33 (1): 25-7.

    AbstractThe authors compare the effects of either 0,5 or one milligram of intrathecally injected morphine on the post-operative course of 45 patients scheduled for transvesical prostatectomy. The patients were randomly assigned to three groups. Group A patients served as reference and were anesthetized by intrathecal injection of prilocaine 100 mg. Group B and C patients underwent the same anaesthetic procedure but prilocaine was injected simultaneously with either 0,5 (B) or one milligram (C) of morphine. Group A patients experienced postoperative pain for eighteen hours and requiring a mean subcutaneous dose of 20 mg of morphine. B and C patients had a satisfactory degree of analgesia. Nevertheless, there was a statistically significant difference of analgesia scores between groups C and B. The group C patients remained free of respiratory impairment. One mg of intrathecal morphine seems optimal for analgesia after prostatectomy.

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