• Thiago César Lima, Elizabete Bagordakis, FalciSaulo Gabriel MoreiraSGMAdjunct Professor, Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Brazil. Electronic address: saulofalci@hotmail.com., Cássio Roberto Rocha Dos Santos, and Marcos Luciano Pimenta Pinheiro.
• MSc Student, Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Brazil.
• J. Oral Maxillofac. Surg. 2018 Jan 1; 76 (1): 60-66.

PurposeWe aimed to compare the effect of dexamethasone, 8 mg, and diclofenac sodium, 50 mg, associated with codeine, 50 mg, on the control of pain, swelling, and trismus after extraction of impacted third molars.Materials And MethodsFifteen healthy patients with a mean age of 22.8 years (SD, 12.62 years) received a single oral dose of either drug 1 hour before each surgical procedure (left and right teeth). At 24, 48, and 72 hours after surgery, swelling was determined by use of linear measurements on the face and trismus was determined by maximal mouth opening. Postoperative pain was self-recorded by the patients using a numerical rating scale at 24-hour intervals for a period of 72 hours. Data analysis involved descriptive statistics and Shapiro-Wilk, Wilcoxon, and paired t tests (P < .05).ResultsDexamethasone controlled pain (P = .016) and edema (P = .08) within 48 hours better than diclofenac sodium associated with codeine. No statistically significant differences were found between drugs regarding trismus and consumption of rescue analgesics (acetaminophen).ConclusionsThe results of this study suggest that pre-emptive administration of dexamethasone, 8 mg, showed better control of pain and swelling in bilateral extractions of third impacted mandibular molars.Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

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