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Clinical Trial Controlled Clinical Trial
Treatment of attacks in hyperkalaemic familial periodic paralysis by inhalation of salbutamol.
- P Wang and T Clausen.
- Lancet. 1976 Jan 31; 1 (7953): 221-3.
AbstractIn fifteen patients with hyperkalaemic familial periodic paralysis, inhalation of salbutamol alleviated hyperkaleamia and paralysis precipitated by exercise or oral administration of potassium chloride. In-vitro studies with rat soleus muscles indicated that the hypokalaemic effect of salbutamol is related to stimulation of the active coupled transport of sodium and potassium in muscle cells. Follow-up studies proved that the inhalation of salbutamol is a simple and adequate method for the treatment of the paralytic episodes in these patients.
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