• Br J Anaesth · Jan 1993

    Effect of isometric thumb preload on the evoked compound muscle action potential.

    • I Kalli.
    • City Maternity Hospital, Department of Anaesthesia, Helsinki, Finland.
    • Br J Anaesth. 1993 Jan 1; 70 (1): 92-3.

    AbstractThe effect of thumb preload on adductor pollicis muscle compound action potential (ECAP) was assessed after supramaximal ulnar nerve stimulus during steady isoflurane anaesthesia in 20 ASA I-II patients without neuromuscular block. During thumb preload, the peak-to-peak amplitude of the ECAP increased by 0.9 mV, to 9.5 (SD 2.2) mV (P < 0.01), because of the increased height of the negative half-wave. The positive half-wave amplitude did not change, but its duration was prolonged by 0.7 ms, to 6.4 (0.7) ms (P < 0.05). Consequently, there was a 15.9% increase in the area of the response curve (P < 0.01). Without preload, the first dorsal interosseus muscle peak-to-peak amplitude was 13.0 (4.3) mV. Thus thumb preload may not be the solution to improved monitoring of neuromuscular block by ECAP.

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