• Expert Rev Neurother · May 2015

    Meta Analysis

    Prognostic value of copeptin in patients with acute stroke.

    • Lidong Jiao, Changbiao Chu, and Shijie Zhou.
    • Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
    • Expert Rev Neurother. 2015 May 1; 15 (5): 563-70.

    ContextThere is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome.ObjectiveTo evaluate the prognostic value of copeptin in patients with stroke.MethodsWe systematically searched PubMed and Embase for relevant studies. Poor outcome and mortality were analyzed.ResultsTwelve studies, containing 2682 patients, were included. Pooled analysis showed that copeptin is an independent prognostic marker of poor outcome after acute stroke and there is a borderline effect of copeptin in predicting mortality after acute stroke.ConclusionsCopeptin is an independent predictor of poor outcome and mortality for patients with acute stroke.

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