• Ricardo Quiroga Díaz, Reynaldo Cantú Mata, Héctor E Tello Gutiérrez, Mireya Puente Villalobos, Rogelio Montemayor Garza, and Araceli Martínez Mendoza.
• Hospital de Ginecología y Obstetricia de Monterrey.
• Ginecol Obstet Mex. 2009 Oct 1; 77 (10): 469-74.

ObjectiveTo evaluate efficacy of misoprostol by intrauterine route for the prevention of the obstetrical hemorrhage and to know its effects collaterals.Patients And MethodsClinical and randomized test with 200 patients to those who one took place to them Caesarean. The Group A was applied placebo and the group B misoprostol (group B; 800 microg) intrauterine, after the birth of its newborns. The necessity of additional uterotonics was compared, loss of hemoglobin and hematocrit, and the effects collaterals.ResultsIn group B it diminished the necessity of additional uterotonics to 50% and the loss of hemoglobin in 39.6%. In the group greater loss of 3 was registered g of hemoglobin in 13 versus 3% of the patients. With respect to the hematocrit, its loss was reduced in 40.6%. The patients in those who the hematocrit in more fell than 10%, registered themselves in 7 versus 1% cases. The effects collaterals were few and not so serious.ConclusionThe intrauterine combination of misoprostol and oxitocin diminishes the postcaesarean sanguineous loss and has brings about few effects collaterals.

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