• Takehiko Kasai, Naofumi Bunya, Kenshiro Wada, Ryuichiro Kakizaki, Hirotoshi Mizuno, Hiroyuki Inoue, Shuji Uemura, Satoshi Takahashi, Eichi Narimatsu, Shinhiro Takeda, and Japan ECMOnet for COVID‐19.
• Department of Emergency Medicine Sapporo Medical University Sapporo Japan.
• Acute Med Surg. 2020 Jan 1; 7 (1): e546.

BackgroundThe efficacy and safety of the combined use of veno-venous extracorporeal membrane oxygenation (ECMO) and prone ventilation are currently not known for coronavirus disease 2019 (COVID-19).Case PresentationWe report two cases in which the combination of veno-venous ECMO and prone ventilation for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia were successfully carried out. Both patients had developed severe respiratory failure due to SARS-CoV-2 pneumonia, thus requiring veno-venous ECMO. Prone ventilation was also administered safely.ConclusionOxygenation and lung compliance gradually improved during prone ventilation, and both patients were successfully extubated. For patients with severe SARS-CoV-2 pneumonia who require veno-venous ECMO, the use of prone ventilation could be beneficial, and should be considered.© 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.

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