• Subashini Srinivasan, Holden H Wu, Kyunghyun Sung, MargolisDaniel J ADJDepartment of Radiological Sciences, University of California, Los Angeles, California, USA., and Daniel B Ennis.
• Department of Radiological Sciences, University of California, Los Angeles, California, USA.
• Magn Reson Med. 2015 Aug 1; 74 (2): 442-51.

PurposeThree-dimensional (3D) T2 -weighted fast spin echo (FSE) imaging of the prostate currently requires long acquisition times. Our objective was to develop a fast 3D T2 -weighted sequence for prostate imaging at 3T using a variable flip angle transition into driven equilibrium (T2 -TIDE) scheme.Methods3D T2 -TIDE uses interleaved spiral-out phase encode ordering to efficiently sample the ky -kz phase encodes and also uses the transient balanced steady-state free precession signal to acquire the center of k-space for T2 -weighted imaging. Bloch simulations and images from 10 healthy subjects were acquired to evaluate the performance of 3D T2 -TIDE compared to 3D FSE.Results3D T2 -TIDE images were acquired in 2:54 minutes compared to 7:02 minutes for 3D FSE with identical imaging parameters. The signal-to-noise ratio (SNR) efficiency was significantly higher for 3D T2 -TIDE compared to 3D FSE in nearly all tissues, including periprostatic fat (45 ± 12 vs. 31 ± 7, P < 0.01), gluteal fat (48 ± 8 vs. 41 ± 10, P = 0.12), right peripheral zone (20 ± 4 vs. 16 ± 8, P = 0.12), left peripheral zone (17 ± 2 vs. 12 ± 3, P < 0.01), and anterior fibromuscular stroma (12 ± 4 vs. 4 ± 2, P < 0.01).Conclusion3D T2 -TIDE images of the prostate can be acquired quickly with SNR efficiency that exceeds that of 3D FSE.© 2014 Wiley Periodicals, Inc.

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