• Wentao Liu, Xuna Zhao, Yajun Ma, Xin Tang, and Jia-Hong Gao.
• Beijing City Key Lab for Medical Physics and Engineering, Institute of Heavy Ion Physics, School of Physics, Peking University, Beijing, China.
• Magn Reson Med. 2016 Jan 1; 75 (1): 280-6.

PurposeA novel k-space reconstruction method is proposed for generating diffusion-weighted imaging (DWI) using navigated interleaved multishot EPI (msEPI).Theory And MethodsIn interleaved msEPI, each shot of data acquired from one coil channel is a subset of the full k-space of that channel. All the k-space subsets of one channel can be treated as an undersampled dataset of a virtual multichannel data, which can be reconstructed by the GRAPPA algorithm after k-space realignment. The intershot phase variations are directly compensated using navigator echoes as the auto-calibrating data in GRAPPA reconstruction. In cases of multichannel msEPI data, all the virtual channels and actual channels can be integrated into a single GRAPPA reconstruction step. The proposed method is tested using both simulation and in-vivo data. The simulation results produced by the proposed method and a SENSE-based method are compared.ResultsThe simulated images generated by the proposed method exhibit less relative error compared with those generated by the SENSE method. Inconsistent shot-to-shot phase variation is naturally resolved by GRAPPA calibration without additional phase map processing. High-quality brain DWI with submillimeter resolution is obtained using our proposed reconstruction method.ConclusionA novel k-space msEPI reconstruction method has been developed for generating high-quality diffusion imaging.© 2015 Wiley Periodicals, Inc.

23 keywords...

hide…