• J Comp Eff Res · Dec 2019

    Reporting and analyses of sex/gender and race/ethnicity in randomized controlled trials of interventions published in the highest-ranking anesthesiology journals.

    • Dinka Begic, Clemens Janda-Martinac, Marija Vrdoljak, and Livia Puljak.
    • Department of Endocrinology, University Clinical Center Tuzla, Tuzla, Bosnia & Hercegovina.
    • J Comp Eff Res. 2019 Dec 1; 8 (16): 1417-1423.

    AbstractAim: We assessed reporting of data on sex/gender and race/ethnicity in randomized controlled trials of interventions published in the highest-ranking anesthesiology journals from 2014 to 2017. Methods: We extracted data regarding terminology for sex/gender, proportion of participants according to the race/gender and race/ethnicity, and results shown for the race/gender and race/ethnicity. Results: Among the analyzed 732 trials, few stratified allocation of participants on the basis of sex/gender and race/ethnicity, few reported results for sex/gender or race/ethnicity and the outcomes reported may be influenced by one or both. Conclusion: In conclusion, outcomes of anesthesiology trials could be vulnerable to an important and avoidable source of bias; trialists need to pay more attention to sex and race/ethnicity when designing and reporting their studies.

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