• Surg. Oncol. Clin. N. Am. · Oct 1997

    Review

    Adjuvant therapy of colorectal cancer.

    • N Kemeny, L Saltz, and A Cohen.
    • Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
    • Surg. Oncol. Clin. N. Am. 1997 Oct 1; 6 (4): 699-722.

    AbstractApproximately 141,000 patients will develop colorectal cancer each year and 45% will have positive lymph nodes, one of the most significant predictors of survival. Now there is evidence that systemic chemotherapy with fluorouracil (FU) and leucovorin, levamisole, or FU and leucovorin with decrease recurrence and increase survival for patients with Dukes' C colon cancer. In patients with Dukes' B or C rectal cancer, combined radiation and FU increase survival and decrease local and distal recurrence.

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