• Prenatal diagnosis · Oct 2017

    Case Reports

    Fetoscopic tracheal occlusion for treatment of non-isolated congenital diaphragmatic hernia.

    • Viola Seravalli, Eric B Jelin, Jena L Miller, Aylin Tekes, Luca Vricella, and Ahmet A Baschat.
    • Center for Fetal Therapy, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    • Prenat. Diagn. 2017 Oct 1; 37 (10): 1046-1049.

    AbstractFetoscopic endotracheal occlusion (FETO) is a prenatal treatment that may increase survival in severe congenital diaphragmatic hernia (CDH). In the USA, FETO is offered for isolated severe left-sided CDH in the context of an FDA-approved feasibility study. FETO in non-isolated cases of severe CDH is only performed with a compassionate use exemption from US regulatory bodies. Anomalies frequently associated with CDH include congenital cystic lesions of the lung and cardiac defects. We describe two cases of non-isolated severe left-sided CDH that underwent prenatal FETO, survived after birth and underwent postnatal surgical repair. The potential benefit of FETO in this setting is discussed. © 2017 John Wiley & Sons, Ltd.© 2017 John Wiley & Sons, Ltd.

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