• Anesthesiology clinics · Jun 2017

    Review

    Novel Anticoagulant Agents in the Perioperative Setting.

    • Allyson Lemay, Alan D Kaye, and Richard D Urman.
    • Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
    • Anesthesiol Clin. 2017 Jun 1; 35 (2): 305-313.

    AbstractAn increasing number of oral anticoagulants have become available over the past decade. Each of these agents has differing implications on both regional and neuraxial anesthetic techniques. This article describes the pharmacology, pharmacokinetics, and pharmacodynamics of the most commonly used novel oral anticoagulants (NOACs). It also outlines recent guidelines for the use of NOACs in the perioperative setting, especially with regard to neuraxial anesthesia.Copyright © 2017 Elsevier Inc. All rights reserved.

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