• Congyu Liao, Ying Chen, Xiaozhi Cao, Song Chen, Hongjian He, Merry Mani, Mathews Jacob, Vincent Magnotta, and Jianhui Zhong.
• Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
• Magn Reson Med. 2017 Mar 1; 77 (3): 1359-1366.

PurposeTo propose a novel reconstruction method using parallel imaging with low rank constraint to accelerate high resolution multishot spiral diffusion imaging.Theory And MethodsThe undersampled high resolution diffusion data were reconstructed based on a low rank (LR) constraint using similarities between the data of different interleaves from a multishot spiral acquisition. The self-navigated phase compensation using the low resolution phase data in the center of k-space was applied to correct shot-to-shot phase variations induced by motion artifacts. The low rank reconstruction was combined with sensitivity encoding (SENSE) for further acceleration. The efficiency of the proposed joint reconstruction framework, dubbed LR-SENSE, was evaluated through error quantifications and compared with ℓ1 regularized compressed sensing method and conventional iterative SENSE method using the same datasets.ResultsIt was shown that with a same acceleration factor, the proposed LR-SENSE method had the smallest normalized sum-of-squares errors among all the compared methods in all diffusion weighted images and DTI-derived index maps, when evaluated with different acceleration factors (R = 2, 3, 4) and for all the acquired diffusion directions.ConclusionRobust high resolution diffusion weighted image can be efficiently reconstructed from highly undersampled multishot spiral data with the proposed LR-SENSE method. Magn Reson Med 77:1359-1366, 2017. © 2016 International Society for Magnetic Resonance in Medicine.© 2016 International Society for Magnetic Resonance in Medicine.

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