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J Pain Symptom Manage · Apr 2005
Randomized Controlled Trial Clinical TrialAcustimulation wrist bands are not effective for the control of chemotherapy-induced nausea in women with breast cancer.
- Joseph A Roscoe, Sara E Matteson, Gary R Morrow, Jane T Hickok, Peter Bushunow, Jennifer Griggs, Raman Qazi, Brian Smith, Zachary Kramer, and Julia Smith.
- University of Rochester Cancer Center, Rochester General Hospital Cancer Center, New York 14642, USA.
- J Pain Symptom Manage. 2005 Apr 1; 29 (4): 376-84.
AbstractThis experiment examined the efficacy of an acustimulation wrist band for the relief of chemotherapy-induced nausea using a randomized three-arm clinical trial (active acustimulation, sham acustimulation, and no acustimulation) in 96 women with breast cancer who experienced nausea at their first chemotherapy treatment. Five outcomes related to wrist band efficacy (acute nausea, delayed nausea, vomiting, QOL, and total amount of antiemetic medication used) were examined. The five outcomes were examined separately using analysis of covariance controlling for age and severity of past nausea. There were no significant differences in any of these study measures among the three treatment conditions (P>0.1 for all). Study results do not support the hypothesis that acustimulation bands are efficacious as an adjunct to pharmacological antiemetics for control of chemotherapy-related nausea in female breast cancer patients.
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