• J-H Kim and Y Lee.
• Yunhwan Lee, MD, DrPH, Department of Preventive Medicine and Public Health, Ajou University School of Medicine, 164 World cup-ro, Youngtong-gu, Suwon 16499, Korea, Tel: +82-31-219-5085; Fax: +82-31-219-5084; E-mail: yhlee@ajou.ac.kr.
• J Nutr Health Aging. 2018 Jan 1; 22 (2): 297-301.

ObjectivesTo investigate the association between stroke and incident dementia in the presence of a competing risk of death.MethodsThis study used the National Health Insurance Service-Senior (NHIS-Senior) claim database from 2002 to 2013 (n = 22,792). Stroke (I69.0-I69.9) and dementia (F01-F03, G30, G31.1) patients were defined by the International Classification of Disease 10th revision. The association of stroke with dementia or death was assessed with Cox proportional hazards model and competing-risk model.ResultsDuring the 10-year follow-up period, there were 1,307 dementia events (5.7%) and 9,272 deaths (40.7%). In the Cox model, the adjusted hazard ratio (HR) for dementia was 2.37 times higher in those who experienced strokes, compared with the non-stroke group (95% CI: 2.23, 2.51). In the presence of death as competing event, stroke was associated with an elevated dementia incidence (HR = 2.06, 95% CI: 1.92, 2.20).ConclusionStroke was significantly associated with an increased risk of incident dementia, with the magnitude of the association being attenuated in the competing risk model.

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