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- Tom W J Scheenen, Dennis W J Klomp, Stefan A Röll, Jurgen J Fütterer, Jelle O Barentsz, and Arend Heerschap.
- Department of Radiology, University Medical Center Nijmegen, Nijmegen, The Netherlands. T.Scheenen@rad.umcn.nl
- Magn Reson Med. 2004 Jul 1; 52 (1): 80-8.
AbstractThe clinical application of 3D proton spectroscopic imaging (3D SI) of the human prostate requires a robust suppression of periprostatic lipid signal contamination, minimal intervoxel signal contamination, and the shortest possible measurement time. In this work, a weighted elliptical sampling of k-space, combined with k-space filtering and pulse repetition time (TR) reduction minimized lipid signals, intervoxel contamination, and measurement time. At 1.5 T, the MR-visible prostate metabolites citrate, creatine, and choline can now be mapped over the entire human prostate with uncontaminated spherical voxels, with a volume down to 0.37 cm3, in measurement times of 7-15 min.Copyright 2004 Wiley-Liss, Inc.
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