• Der Internist · Aug 2021

    Review

    [Diagnostics and treatment of statin-associated muscle symptoms].

    • Ursula Kassner, Stefanie Grunwald, Dominik Spira, Nikolaus Buchmann, Thomas Bobbert, Elisabetta Gazzerro, Tim Hollstein, Simone Spuler, and Elisabeth Steinhagen-Thiessen.
    • Lipidambulanz, Klinik für Endokrinologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. elisabeth.steinhagen-thiessen@gmx.de.
    • Internist (Berl). 2021 Aug 1; 62 (8): 827-840.

    AbstractStatins are among the most frequently prescribed drugs in Germany. Their benefits in lowering cardiovascular risk are beyond dispute. Nevertheless, many patients complain of side effects from statin therapy, including statin-associated muscle symptoms (SAMS) in particular. Despite their relative frequency, it is difficult to objectively diagnose them, as the time until appearance of first symptoms, the nature of the complaints and the severity of muscle problems vary widely. This narrative review summarizes the causes of SAMS as well as new possibilities regarding their diagnosis and therapy.© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

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