• Ann Vasc Surg · Jan 2015

    Review Case Reports

    Successful treatment of a mycotic multifocal thoracoabdominal aortic aneurysm as a late sequelae of intravesical bacillus Calmette-Guerin therapy: case report and literature review.

    • Frank M Davis, David J Miller, Duane Newton, Shipra Arya, and Guillermo A Escobar.
    • Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI.
    • Ann Vasc Surg. 2015 Jan 1; 29 (4): 840.e9-13.

    AbstractBacillus Calmette-Guerin (BCG) is a live, attenuated strain of Mycobacterium bovis commonly used for the treatment of superficial bladder carcinoma. Intravesical BCG is well tolerated despite side effects that range from hematuria to sepsis syndrome. A very rare complication is vascular infection developing a mycotic BCG aneurysm, especially in the thoracoabdominal aorta (TAAA). These are challenging to diagnose because of their scarcity, nontraditional culture media, slow growth, and are often lethal. We report the first successful repair of a symptomatic, multifocal TAAA secondary to M bovis manifesting 17 months after intravesical BCG therapy and review the literature. Copyright © 2015 Elsevier Inc. All rights reserved.

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