• José Manuel Fernández Ibáñez, María Del Carmen Morales Ballesteros, Manuel José Fernández Anguita, María Ángeles Galindo Andúgar, Ángel Arias Arias, and José Ramón Barberá-Farré.
• Servicio de Medicina Interna. Sección Geriatría. Hospital General Mancha Centro, Alcázar de San Juan, España. Electronic address: jmfernandezi@sescam.jccm.es.
• Med Clin (Barc). 2022 Jun 24; 158 (12): 603607603-607.

Background And ObjectiveThe COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors.Materials And MethodsRetrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors.Results410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR: 1.55 (95%CI: 0.96 - 2.48; p=0.071)]. Increasing hospital mortality was associated with older age [OR: 1.05 (95% CI 1.02-1.07), per year increase; p<0.001)], Charlson ≥3 [OR: 1.84 (95%CI: 1.07-3.15, p=0.027)] and heart failure on admission [OR: 6 (IC95%: 1.6 - 21.7; p=0.007)] CONCLUSIONS: Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

22 keywords...

hide…