• Edward J Auerbach, Junqian Xu, Essa Yacoub, Steen Moeller, and Kâmil Uğurbil.
• Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA. eja@umn.edu
• Magn Reson Med. 2013 May 1; 69 (5): 1261-7.

PurposeTo evaluate an alternative method for generating multibanded radiofrequency (RF) pulses for use in multiband slice-accelerated imaging with slice-GRAPPA unaliasing, substantially reducing the required peak power without bandwidth compromises. This allows much higher accelerations for spin-echo methods such as SE-fMRI and diffusion-weighted MRI where multibanded slice acceleration has been limited by available peak power.Theory And MethodsMultibanded "time-shifted" RF pulses were generated by inserting temporal shifts between the applications of RF energy for individual bands, avoiding worst-case constructive interferences. Slice profiles and images in phantoms and human subjects were acquired at 3 T.ResultsFor typical sinc pulses, time-shifted multibanded RF pulses were generated with little increase in required peak power compared to single-banded pulses. Slice profile quality was improved by allowing for higher pulse bandwidths, and image quality was improved by allowing for optimum flip angles to be achieved.ConclusionA simple approach has been demonstrated that significantly alleviates the restrictions imposed on achievable slice acceleration factors in multiband spin-echo imaging due to the power requirements of multibanded RF pulses. This solution will allow for increased accelerations in diffusion-weighted MRI applications where data acquisition times are normally very long and the ability to accelerate is extremely valuable.Copyright © 2013 Wiley Periodicals, Inc.

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