• Hong Kong Med J · Oct 2016

    Review

    Extracorporeal blood purification for sepsis.

    • H P Shum, W W Yan, and T M Chan.
    • Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
    • Hong Kong Med J. 2016 Oct 1; 22 (5): 478-85.

    AbstractIt has been speculated that extracorporeal blood purification therapies might improve the clinical outcome for patients with severe sepsis, with or without acute kidney injury, since the removal of inflammatory mediators and/or bacterial toxins from circulation could modulate the inflammatory responses that result in organ damage. Despite initial enthusiasm based on promising preliminary results, subsequent investigations did not show sustainable survival benefit. We review the principles and development of blood purification techniques for sepsis and septic acute kidney injury.

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