• Y-C K Huang, T-Y Huang, H-C Chiu, T-S Kuo, C-J Hsueh, H-W Kao, C-W Wang, H-H Hsu, and C-J Juan.
• From the Department of Electrical Engineering (Y.-C.K.H., T.-S.K.), National Taiwan University, Taipei, Taiwan, Republic of ChinaDepartment of Radiology (Y.-C.K.H., C.-J.H., H.-W.K, C.-W.W., H.-H. H., C.-J.J.), Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
• AJNR Am J Neuroradiol. 2014 Jun 1; 35 (6): 1137-44.

Background And PurposeCurrent T2-weighted imaging takes >3 minutes to perform, for which the ultrafast transition into driven equilibrium (TIDE) technique may be potentially helpful. This study qualitatively and quantitatively evaluates the imaging of transition into driven equilibrium of the balanced steady-state free precession (TIDE) compared with TSE and turbo gradient spin-echo on T2-weighted MR images.Materials And MethodsThirty healthy volunteers were examined with T2-weighted images by using TIDE, TSE, and turbo gradient spin-echo sequences. Imaging was evaluated qualitatively by 2 independent observers on the basis of a 4-point rating scale regarding contrast characteristics and artifacts behavior. Image SNR and contrast-to-noise ratio were quantitatively assessed.ResultsTIDE provided T2-weighted contrast similar to that in TSE and turbo gradient spin-echo with only one-eighth of the scan time. TIDE showed gray-white matter differentiation and iron-load sensitivity inferior that of TSE and turbo gradient spin-echo, but with improved motion artifacts reduction on qualitative scores. Nonmotion ghosting artifacts were uniquely found in TIDE images. The overall SNRs of TSE were 1.9-2.0 times those of turbo gradient spin-echo and 1.7-2.2 times of those of TIDE for brain tissue (P < .0001). TIDE had a higher contrast-to-noise ratio than TSE (P = .169) and turbo gradient spin-echo (P < .0001) regarding non-iron-containing gray matter versus white matter. TIDE had a lower contrast-to-noise ratio than turbo gradient spin-echo and TSE (P < .0001) between iron-containing gray matter and white matter.ConclusionsTIDE provides T2-weighted images with reduced scan times and reduced motion artifacts compared with TSE and turbo gradient spin-echo with the trade-off of reduced SNR and poorer gray-white matter differentiation.© 2014 by American Journal of Neuroradiology.

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