• Pamela E Houghton, Karen E Campbell, Christine H Fraser, Connie Harris, David H Keast, Patrick J Potter, Keith C Hayes, and M Gail Woodbury.
• Rehabilitation and Geriatric Care Center, Lawson Health Research Institute, London, Ontario, Canada. phoughto@uwo.ca <phoughto@uwo.ca>
• Arch Phys Med Rehabil. 2010 May 1; 91 (5): 669-78.

ObjectiveTo investigate whether electric stimulation therapy (EST) administered as part of a community-based, interdisciplinary wound care program accelerates healing of pressure ulcers in people with spinal cord injury (SCI).DesignSingle-blind, parallel-group, randomized, controlled, clinical trial.SettingCommunity-based home care setting, Ontario, Canada.ParticipantsAdults (N=34; mean age +/- SD, 51+/-14y) with SCI and stage II to IV pressure ulcers.InterventionsSubjects were stratified based on wound severity and duration and randomly assigned to receive either a customized, community-based standard wound care (SWC) program that included pressure management or the wound care program plus high-voltage pulsed current applied to the wound bed (EST+SWC).Main Outcome MeasuresWound healing measured by reduction in wound size and improvement in wound appearance at 3 months of treatment with EST+SWC or SWC.ResultsThe percentage decrease in wound surface area (WSA) at the end of the intervention period was significantly greater in the EST+SWC group (mean +/- SD, 70+/-25%) than in the SWC group (36+/-61%; P=.048). The proportion of stage III, IV, or X pressure ulcers improving by at least 50% WSA was significantly greater in the EST+SWC group than in the SWC group (P=.02). Wound appearance assessed using the photographic wound assessment tool was improved in wounds treated with EST+SWC but not SWC alone.ConclusionsThese results demonstrate that EST can stimulate healing of pressure ulcers of people with SCI. EST can be incorporated successfully into an interdisciplinary wound care program in the community.

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