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Rev Stomatol Chir Maxillofac · Jan 1995
[Cervicofacial involvement of primary cutaneous neuroendocrine carcinomas or Merkel cell tumors: therapeutic considerations].
- S de Mortillet, B Laurent, E Fassio, F Zimmann, B Bonin, J Brie, D Goga, and G Ballon.
- Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Trousseau, Tours.
- Rev Stomatol Chir Maxillofac. 1995 Jan 1; 96 (1): 33-5.
AbstractSeven cases of primary skin neuroendocrine carcinoma or Merkel cell tumours with cervico-facial localization are reported. The poor prognosis of these tumours is essentially due to the potential for local recurrence and the frequency of locoregional and visceral metastasis. Surgical treatment is required but rarely sufficient to control the disease. Complementary radiotherapy, when performed early, can reduce the rate of locoregional recurrence. Lymph node resection is important to determine prognosis but has not been proven to improve outcome. In addition, parotid metastasis appears to result from blood stream dissemination and has a very poor prognosis. Exclusive radiotherapy may be discussed in such cases.
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