• Cardiology clinics · Aug 2015

    Review

    Syncope and Idiopathic (Paroxysmal) AV Block.

    • Michele Brignole, Jean-Claude Deharo, and Regis Guieu.
    • Department of Cardiology, Arrhythmologic Center, Ospedali del Tigullio, Via Don Bobbio 25, Lavagna 16033, Italy. Electronic address: mbrignole@ASL4.liguria.it.
    • Cardiol Clin. 2015 Aug 1; 33 (3): 441-7.

    AbstractSyncope due to idiopathic AV block is characterized by: 1) ECG documentation (usually by means of prolonged ECG monitoring) of paroxysmal complete AV block with one or multiple consecutive pauses, without P-P cycle lengthening or PR interval prolongation, not triggered by atrial or ventricular premature beats nor by rate variations; 2) long history of recurrent syncope without prodromes; 3) absence of cardiac and ECG abnormalities; 4) absence of progression to persistent forms of AV block; 5) efficacy of cardiac pacing therapy. The patients affected by idiopathic AV block have low baseline adenosine plasma level values and show an increased susceptibility to exogenous adenosine. The APL value of the patients with idiopathic AV block is much lower than patients affected by vasovagal syncope who have high adenosine values. Copyright © 2015 Elsevier Inc. All rights reserved.

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