• Spec Care Dentist · Jul 2010

    Case Reports

    Necrotizing sialometaplasia in a patient who is HIV positive: a case report.

    • Alessandra Dutra Silva, Carolina Amália Barcellos Silva, Cristiane Furuse, Rodrigo Calado Nunes e Souza, Mauro Henrique Melo da Costa, and Vera Cavalcanti de Araújo.
    • Institute and Research Center São Leopoldo Mandic, Campinas, São Paulo, Brazil. alessandradutrasilva@hotmail.com
    • Spec Care Dentist. 2010 Jul 1; 30 (4): 160-2.

    AbstractNecrotizing sialometaplasia (NS) is a self-limiting, benign, inflammatory disease of the minor salivary glands of the hard palate. The main significance of the NS lesion lies in the fact that it may be mistaken for mucoepidermoid or squamous cell carcinoma. A case report is presented of a patient with NS who was HIV positive; the lesion was located in the minor salivary glands of the hard palate. Clinically, the lesion presented as a deep ulcer with slightly elevated irregular borders and a necrotic base in the hard palate. Histologically, the tissue was characterized by squamous metaplasia of ducts and acini, lobular coagulation necrosis, and pseudoepitheliomatous hyperplasia of the overlying epithelium. The lesion disappeared completely after 2 weeks.

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