• Gastroenterol. Clin. North Am. · Mar 2010

    Review

    Hepatic complications of obesity.

    • Anna Mae Diehl.
    • Department of Medicine, Division of Gastroenterology, Duke University, Durham, NC 27710, USA. diehl004@mc.duke.edu
    • Gastroenterol. Clin. North Am. 2010 Mar 1; 39 (1): 57-68.

    AbstractObesity is associated with a spectrum of chronic liver disease. Because obesity increases the risk for advanced forms of liver disease (ie, cirrhosis and liver cancer), the obesity epidemic is emerging as a major factor underlying the burden of liver disease in the United States and many other countries. This article reviews mechanisms that mediate the pathogenesis of obesity-related liver disease, summarizes clinical evidence that demonstrates obesity-related liver disease can be life-threatening, and discusses whether or not treatments for obesity or related comorbidities impact liver disease outcomes.Copyright (c) 2010 Elsevier Inc. All rights reserved.

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