• W C Lineaweaver, H Furnas, S Follansbee, G H Buncke, T M Whitney, F Canales, R Bruneteau, and H J Buncke.
• Microsurgical Replantation Transplantation Department, Davies Medical Center, San Francisco, CA 94114.
• Ann Plast Surg. 1992 Sep 1; 29 (3): 245-9.

AbstractIncreasing use of medicinal leeches has been accompanied by increasing numbers of reports of Aeromonas hydrophila infections after leech application on or near damaged tissue. We examined the enteric contents of postprandial leeches after their application to patients receiving antibiotics. We found measurable levels of antibiotic in the leech enteric contents, and in leeches applied to patients receiving an antibiotic effective against Aeromonas hydrophila, there was a significant decrease in positive Aeromonas enteric cultures. Suppression of leech enteric bacteria by antibiotic administration to the patient may be an effective strategy to prevent invasive infection by Aeromonas hydrophila as well as bacterial colonization of devitalized tissue that could be the source of late infection. Clinical studies will be required to clarify whether suppression of leech enteric flora results in a decrease in infections associated with leech use.

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