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Randomized Controlled Trial
Theta burst stimulation of the motor cortex reduces laser-evoked pain perception.
- Csaba Poreisz, Gábor Csifcsák, Andrea Antal, Maik Levold, Ferdinand Hillers, and Walter Paulus.
- Department of Clinical Neurophysiology, Georg-August University, Göttingen, Germany. csaba.poreisz@med.uni-goettingen.de
- Neuroreport. 2008 Jan 22; 19 (2): 193-6.
AbstractRepetitive transcranial magnetic stimulation over the primary motor cortex (M1) was recently introduced to modulate pain perception. The aim of this double-blind cross-over study was to investigate the effect of a modified rTMS paradigm, called cTBS on experimentally induced laser-evoked pain applied over the left M1. cTBS inhibits the cortical excitability of the M1 for approximately 1 h. Subjective pain was measured using the verbal analogue scale prior to, immediately after and 30 min post-stimulation. cTBS, and not the sham stimulation resulted in a significant decrease in pain perception on both hands, accentuated on the right hand. Further studies are needed using motor cortex TBS in chronic pain to pave the way towards a therapeutic tool.
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