• J Magn Reson Imaging · Dec 2002

    Dynamic contrast-enhanced myocardial perfusion imaging using saturation-prepared TrueFISP.

    • Wolfgang Günther Schreiber, Melanie Schmitt, Peter Kalden, Oliver Klaus Mohrs, Karl-Friedrich Kreitner, and Manfred Thelen.
    • Department of Radiology, Johannes Gutenberg-University, Mainz, Germany. wolfgang.schreiber@radiologie.klinik.uni-mainz.de
    • J Magn Reson Imaging. 2002 Dec 1; 16 (6): 641-52.

    PurposeTo develop and test a saturation-recovery TrueFISP (SR-TrueFISP) pulse sequence for first-pass myocardial perfusion imaging.Materials And MethodsFirst-pass magnetic resonance imaging (MRI) of Gd-DTPA (2 mL) kinetics in the heart was performed using an SR-TrueFISP pulse sequence (TR/TE/alpha = 2.6 msec/1.4 msec/55 degrees ) with saturation preparation TD = 30 msec before the TrueFISP readout. Measurements were also performed with a conventional saturation-recovery TurboFLASH (SRTF) pulse sequence for comparison.ResultsSR-TrueFISP images were of excellent quality and demonstrated contrast agent wash-in more clearly than SRTF images. The signal increase in myocardium was higher in SR-TrueFISP than in SRTF data. Precontrast SNR and peak CNR were not significantly different between both sequences despite 57% improved spatial resolution for SR-TrueFISP.ConclusionSR-TrueFISP first-pass MRI of myocardial perfusion leads to a substantial improvement of image quality and spatial resolution. It is well suited for first-pass myocardial perfusion studies at cardiovascular MR systems with improved gradient hardware.Copyright 2002 Wiley-Liss, Inc.

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