• Perspect. Biol. Med. · Jan 2006

    Historical Article

    Dietary treatment of diabetes mellitus in the pre-insulin era (1914-1922).

    • Eric C Westman, William S Yancy, and Margaret Humphreys.
    • Division of General Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA. ewestman@duke.edu
    • Perspect. Biol. Med. 2006 Jan 1; 49 (1): 77-83.

    AbstractBefore the discovery of insulin, one of the most common dietary treatments of diabetes mellitus was a high-fat, low-carbohydrate diet. A review of Frederick M. Allen's case histories shows that a 70% fat, 8% carbohydrate diet could eliminate glycosuria among hospitalized patients. A reconsideration of the role of the high-fat, low-carbohydrate diet for the treatment of diabetes mellitus is in order.

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