• James W Brantingham, Debra Bonnefin, Stephen M Perle, Tammy Kay Cassa, Gary Globe, Mario Pribicevic, Marian Hicks, and Charmaine Korporaal.
• Cleveland Chiropractic College, Los Angeles, CA, USA. Jimbrant2002@yahoo.com
• J Manipulative Physiol Ther. 2012 Feb 1; 35 (2): 127-66.

ObjectiveThe purpose of this study is to update a systematic review on manipulative therapy (MT) for lower extremity conditions.MethodsA review of literature was conducted using MEDLINE, MANTIS, Science Direct, Index to Chiropractic Literature, and PEDro from March 2008 to May 2011. Inclusion criteria required peripheral diagnosis and MT with or without adjunctive care. Clinical trials were assessed for quality using a modified Scottish Intercollegiate Guidelines Network (SIGN) ranking system.ResultsIn addition to the citations used in a 2009 systematic review, an additional 399 new citations were accessed: 175 citations in Medline, 30 citations in MANTIS, 98 through Science Direct, 54 from Index to Chiropractic Literature, and 42 from the PEDro database. Forty-eight clinical trials were assessed for quality.ConclusionsRegarding MT for common lower extremity disorders, there is a level of B (fair evidence) for short-term and C (limited evidence) for long-term treatment of hip osteoarthritis. There is a level of B for short-term and C for long-term treatment of knee osteoarthritis, patellofemoral pain syndrome, and ankle inversion sprain. There is a level of B for short-term treatment of plantar fasciitis but C for short-term treatment of metatarsalgia and hallux limitus/rigidus and for loss of foot and/or ankle proprioception and balance. Finally, there is a level of I (insufficient evidence) for treatment of hallux abducto valgus. Further research is needed on MT as a treatment of lower extremity conditions, specifically larger trials with improved methodology.Copyright © 2012 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

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