• Clin Plast Surg · Oct 2017

    Review

    Peripheral Neuropathy and Nerve Compression Syndromes in Burns.

    • Amy L Strong, Shailesh Agarwal, Paul S Cederna, and Benjamin Levi.
    • Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
    • Clin Plast Surg. 2017 Oct 1; 44 (4): 793-803.

    AbstractPeripheral neuropathy and nerve compression syndromes lead to substantial morbidity following burn injury. Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy. The symptoms manifest at various times from within one week of hospitalization to many months after wound closure. Peripheral neuropathy may be caused by vascular occlusion of vasa nervorum, inflammation, neurotoxin production leading to apoptosis, and direct destruction of nerves from the burn injury. This article discusses the natural history, diagnosis, current treatments, and future directions for potential interventions for peripheral neuropathy and nerve compression syndromes related to burn injury.Copyright © 2017 Elsevier Inc. All rights reserved.

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