• Marie Thomas, Maximilian Kreibich, Friedhelm Beyersdorf, Christoph Benk, Sven Maier, and Georg Trummer.
• Department for Cardiovascular Surgery, Universitäts-Herzzentrum Freiburg Bad Krozingen GmbH, Freiburg, Baden-Württemberg, Germany.
• Thorac Cardiovasc Surg. 2020 Aug 1; 68 (5): 425-432.

ObjectivesSeparation from extracorporeal life support (ECLS) is often based on individual decisions rather than evaluated standard operating procedures (SOPs). Therefore, we strived to evaluate a SOP, summarizing specific treatment paths for this group of patients.MethodsA total of 107 cardiovascular patients were supported with ECLS within a 4-year period. Fifty-three patients were treated before the SOP was introduced (group A) and 54 patients were treated afterward (group B). Patient characteristics and outcomes were analyzed and compared between the two time periods regarding baseline characteristics, compliance with SOP criteria, and the end points successful weaning and 30-day survival.ResultsSuccessful weaning rose significantly from 56.6 to 74.1% (p = 0.045) and 30-day survival rate increased from 34.0 to 50.0% (p = 0.069) after implementation of the SOP. Successful weaning was significantly associated with daily echocardiography (p = 0.012) and circulatory support with dobutamine (p = 0.026). The investigated other criteria used in the weaning process did not show a significant correlation with better outcome.ConclusionThe SOP for ECLS weaning showed higher weaning rates compared with a weaning based on individual decisions. Although only parts of the SOP were associated with higher weaning and survival rates, the SOP was experienced as a useful guideline for standardized ECLS management.Georg Thieme Verlag KG Stuttgart · New York.

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