• Int. J. Clin. Pract. · Oct 2021

    Immediate Effect Of Inhalation Therapy Combined With Oscillatory Positive Expiratory Pressure On The Respiratory System Of Children With Cystic Fibrosis.

    • Gonçalves WamosyRenata MabaRMhttps://orcid.org/0000-0001-5772-9650University of the State of Santa Catarina (UDESC), Florianópolis, Santa Catarina, Brazil., Tayná Castilho, Ana Carolina da Silva Almeida, Maíra Seabra de Assumpção, Norberto Ludwig Neto, and SchivinskiCamila Isabel SantosCIShttps://orcid.org/0000-0002-6139-9727University of the State of Santa Catarina (UDESC), Florianópolis, Santa Catarina, Brazil.State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil..
    • University of the State of Santa Catarina (UDESC), Florianópolis, Santa Catarina, Brazil.
    • Int. J. Clin. Pract. 2021 Oct 1; 75 (10): e14659.

    IntroductionIt is recommended the association of inhalation therapies and physiotherapy on the management of cystic fibrosis (CF); however, it is still necessary to understand the effect on respiratory mechanics of these therapies combined. This study aimed to evaluate the immediate effect of inhalation with Dornase-Alfa (DNase) and hypertonic saline solution (HSS), as well as the impact of these inhalation therapies associated with an oral high-frequency oscillation (OHFO) physiotherapy device, on the respiratory mechanics of children and adolescents with CF.MethodChildren/adolescents with CF were allocated into two groups (DNaseG and HSSG), where they performed inhalation therapy before using the OHFO device for physiotherapy. In each group, the Impulse Oscillometry System was conducted before and after inhalation therapy, and after OHFO. ANOVA was carried out to analyse the respiratory mechanics at different moments of DNaseG and HSSG. The Mann-Whitney test compared the immediate effect of each inhalation therapy and after OHFO.Results30 children (6-14 years old) were studied. In DNaseG, the mean value of most oscillometric parameters decreased in the evaluated moments; in HSSG, only reactance showed an immediate increase.ConclusionChildren/adolescents with CF showed an immediate decrease in airway resistance and reactance after the use of DNase and associated with OHFO, indicating improvement. The inhalation with HSS has an immediate effect on peripheral airways.© 2021 John Wiley & Sons Ltd.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.