• Florian Fuchsgruber, Lisa Tölke, and Patrick Friederich.
• Klinik für Anaesthesiologie, operative Intensivmedizin und Schmerztherapie, München Klinik Bogenhausen, Lehrkrankenhaus der technischen Universität München, Englschalkinger Straße 77, 81925, München, Deutschland. Florian.Fuchsgruber@muenchen-klinik.de.
• Anaesthesist. 2022 Mar 1; 71 (3): 201-209.

BackgroundDespite numerous studies on the regional cerebral oxygen saturation (rSO2) measured by near infrared spectroscopy (NIRS) in orthopedic patients in the beach chair position, it is still unclear whether patient-specific factors, such as concomitant cardiovascular diseases, are more frequently associated with the occurrence of cerebral desaturation events (CDE).ObjectiveThe aim of the present study was therefore to identify possible patient-specific risk factors that enable prediction of CDE.MethodsData were collected on 397 orthopedic patients undergoing shoulder surgery in the beach chair position. Routine anesthesia management and standard monitoring was used in all patients. Target value for the inspiratory oxygen concentration (FIO2) was set to 50% and for the end-tidal carbon dioxide partial pressure to 35-45 mm Hg. RSO2 was quantified using NIRS. The responsible anesthesiologist was blinded to the rSO2 data. A decrease in rSO2 > 20% or a value < 50% in the beach chair position was defined as CDE. Patients with and without CDE were analyzed with respect to different classifications, American Society of Anesthesiologists (ASA) and Revised Cardiac Risk Index (RCRI) as well as existing arterial hypertension and age. A value of p <0.05 was considered statistically significant.ResultsPatients with CDE (n = 238) were significantly more often classified as ASA > 2 (p = 0.01) and RCRI > 1 (p = 0.01), suffered more often from arterial hypertension (p = 0.01) and were older (median: 60 years compared to 55 years; p = 0.01) than patients without CDE (n = 159) in the beach chair position (Wilcoxon rank sum test). Arterial hypertension remained significant after removing the effect of age (p = 0.03) and RCRI classification (p = 0.04; two-way ANOVA multivariate analysis).ConclusionOn the basis of our study, patient-specific prognosis and risk factors for the occurrence of CDE, such as higher age, ASA > 2 and RCRI > 1 classification as well as pre-existing arterial hypertension could be determined. Arterial hypertension represents the main risk factor for the occurrence of CDE in the beach chair position. RCRI > 1 classification or age, however, only has an effect on the occurrence of pathological rSO2 values due to the greater probability of simultaneous arterial hypertension.© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

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