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- Ramona Bonometti, Mattia Bellan, Daniele Sola, Antonello Gibbin, Francesco Gavelli, Filippo Patrucco, Paolo Spina, Alessandro Gualerzi, Serena Favretto, Luigi Mario Castello, Pier Paolo Sainaghi, and Mario Pirisi.
- Division of Internal Medicine, AOU Maggiore della Carità, Novara, Italy.
- Natl Med J India. 2020 Nov 1; 33 (6): 344-346.
AbstractMulticentric Castleman disease (MCD) is a rare clinical entity characterized by a polyclonal lymphoid proliferation, leading to generalized lymphadenopathy, organomegaly and systemic symptoms. It has been reported in association with either other monoclonal or polyclonal lymphoid disorders, such as POEMS syndrome and immunoglobulin (Ig)G4-related disease. We present a patient showing a variant of MCD, sharing common features with POEMS syndrome and associated with the proliferation of IgG4-producing plasma cells.
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